Drug Name Abilify

A quick-dissolving tablet (also known as a fast-dissolving, fast-dissolving multiparticulate, rapid-dissolving, mouth-dissolving, fastmelting, or orodispersing tablets) is an oral tablet that does not require water for swallowing. The tablet dissolves within 60 seconds when placed in the mouth.
By stimulating ?1-receptors, hence activation of adenylatcyclase (Ad-cyclase) and cAMP production, catecholamines augment all heart functions, including systolic force (positive inotropism), velocity of shortening (p. clinotropism), sinoatrial rate (p. chronotropism), conduction velocity (p. dromotropism), and excitability (p. bathmotropism).

 

Factors determining oxygen demand. The heart muscle cell consumes the most energy to generate contractile force. O2 demand rises with an increase in (1) heart rate, (2) contraction velocity, (3) systolic wall tension (“afterload”). The latter depends on ventricular volume and the systolic pressure needed to empty the ventricle.
Disintegration test The time for disintegration of ODTs is generally less than one minute and actual disintegration time that patient can experience ranges from 5-30 seconds. The standard procedure of performing disintegration test for these dosage forms has several limitations and they are not suitable for the measurement of very short disintegration times.